OSA is estimated to occur in 8 - 10,000 dogs per year in the United States, and it is highly malignant. (Tending to infiltrate, metastasize, and terminate fatally )
Cancerous lesions of the bone present most commonly between 2-8 years of age, with 7 years being the average age for presentation
According to the bone tumor database at the Animal Cancer Center at Colorado State University, 98% of 1,273 appendicular primary bone tumors diagnosed in dogs were OSA.
Osteosarcoma can develop in any bone but the limbs account for 75-85% of affected bones. The front legs are affected twice as often as the hind legs.
Giant breeds have a greater risk for developing Osteosarcoma, and males have a slightly higher risk than females for this form of cancer.
With local disease control alone (amputation or limb sparing), the 1 year survival rate is les than 10%, and most patients succumb to pulmonary metastasis. (Relating to or affecting the lungs)